Droxaryl Cream 20g (Bufexamac 5%)

Description

Detailed Note on Droxaryl Cream

Overview

Droxaryl Cream is a topical medication commonly used to treat a variety of skin conditions, primarily those associated with bacterial infections and inflammation. It contains Cefadroxil, a broad-spectrum antibiotic that effectively combats bacterial infections on the skin. The cream is often recommended for the treatment of conditions such as infected wounds, boils, impetigo, and other skin infections caused by susceptible bacteria.

Composition

• Active Ingredient: Cefadroxil (A first-generation cephalosporin antibiotic)
• Excipients: May include stabilizers, emulsifiers, and preservatives for cream formulation.

Uses

Droxaryl Cream is indicated for the treatment of:

• Bacterial Skin Infections: Such as impetigo, cellulitis, and infected dermatitis.
• Wound Infections: Prevents and treats bacterial infection in cuts, burns, or surgical wounds.
• Boils and Abscesses: Helps reduce bacterial growth in localized infections.
• Skin Ulcers and Erosions: Prevents infection in skin lesions, promoting faster healing.

Mechanism of Action

Cefadroxil, the active ingredient in Droxaryl Cream, works by:

• Inhibiting Bacterial Cell Wall Synthesis: It binds to bacterial enzymes called penicillin-binding proteins (PBPs), preventing the formation of the bacterial cell wall.
• Bactericidal Effect: Leads to bacterial cell death, effectively eliminating the infection.

This makes Droxaryl Cream particularly effective against Gram-positive bacteria like Staphylococcus aureus and Streptococcus pyogenes, which are common causes of skin infections.

Dosage and Administration

• Frequency: Apply 2 to 3 times daily or as directed by a healthcare provider.
• Application:
  • Clean and dry the affected area before applying the cream.
  • Apply a thin layer of Droxaryl Cream over the infected skin.
  • Gently massage until absorbed.
  • Wash hands thoroughly after application.
• Duration: Use for the entire prescribed period, even if symptoms improve, to prevent recurrence of infection.

Precautions and Warnings

• For External Use Only: Avoid contact with eyes, nose, mouth, and open wounds.
• Allergic Reactions: Do not use if allergic to cefadroxil, cephalosporins, or penicillin.
• Pregnancy and Lactation: Consult a doctor before use.
• Underlying Conditions: Inform your healthcare provider if you have kidney disease or a history of antibiotic allergies.
• Avoid Overuse: Prolonged use may lead to antibiotic resistance.

Side Effects

While Droxaryl Cream is generally well-tolerated, some users may experience:

• Mild skin irritation, redness, or itching.
• Dry or peeling skin.
• Burning or stinging sensation.
• Allergic reactions in rare cases, such as rash, swelling, or difficulty breathing.

Seek immediate medical attention if severe allergic reactions occur.

Storage

• Store at room temperature (20-25°C).
• Keep away from direct sunlight and moisture.
• Keep out of reach of children.

Additional Tips

• Clean the affected area properly before applying the cream to maximize effectiveness.
• Avoid applying on severely damaged or broken skin unless directed by a doctor.
• Complete the full course of treatment to prevent the development of antibiotic resistance.
• If no improvement is seen within 7 days, consult your healthcare provider for further evaluation.