Gynosporin Vagnial Cream (Clotrimazole Vaginal Cream)

Description

Gynosporin Vaginal Cream – Detailed Note

Overview

Gynosporin Vaginal Cream is a topical antifungal medication primarily used for the treatment of vaginal yeast infections, particularly caused by the fungus Candida. It contains Clotrimazole as its active ingredient, which is an imidazole antifungal agent. Clotrimazole works by inhibiting the growth of fungi by disrupting their cell membranes.

Composition

• Active Ingredient: Clotrimazole (1% or 2%)
• Excipients: May include cetostearyl alcohol, mineral oil, polysorbate, and purified water.
• Available in cream form for intravaginal application, often accompanied by an applicator.

Uses

• Treatment of vulvovaginal candidiasis (yeast infection).
• Relief from symptoms like vaginal itching, burning, discharge, and irritation.
• Sometimes recommended as part of combination therapy for recurrent fungal infections.

Mechanism of Action

Clotrimazole works by:

• Binding to fungal cell membranes.
• Inhibiting the synthesis of ergosterol, an essential component of the fungal cell membrane.
• Causing increased permeability, leakage of cellular components, and ultimately fungal cell death.

Dosage and Administration

• Gynosporin Vaginal Cream 1%: Usually applied once daily for 7 days.
• Gynosporin Vaginal Cream 2%: Applied once daily for 3 days.
• Administer using the provided applicator, inserting the cream high into the vagina.
• It is generally recommended to apply it at bedtime to minimize leakage.

Precautions and Warnings

• Pregnancy and Lactation: Consult a doctor before use. It is generally considered safe during pregnancy under supervision.
• Allergic Reactions: Avoid if allergic to clotrimazole or other azole antifungals.
• Drug Interactions: Minimal systemic absorption, but inform the doctor about other medications.
• Medical Conditions: Exercise caution in cases of recurrent infections or underlying medical conditions like diabetes or immune deficiencies.
• Sexual Activity: Avoid sexual intercourse during treatment as the cream may weaken latex condoms or diaphragms.

Side Effects

Some users may experience:

• Mild vaginal irritation, itching, or burning.
• Abdominal cramps.
• Increased vaginal discharge.
• Allergic reactions like rash or hives (rare).

If severe symptoms occur, medical attention is required.

Storage

• Store at room temperature (20-25°C).
• Keep away from direct sunlight and moisture.
• Ensure the tube is tightly closed when not in use.

Additional Tips

• Maintain proper hygiene and wear breathable cotton underwear to prevent fungal growth.
• Complete the full course of treatment even if symptoms resolve early.
• Avoid douching, scented feminine products, or harsh soaps during treatment.
• Seek medical advice if symptoms persist or worsen after treatment.