Centaurus Tablets 0.5mg (Entecavir Tablets u.s.p) 30 Film Coated Tablets
Centaurus Tablets: Description
Centaurus 0.5 mg Tablets contain Entecavir as the active ingredient. Entecavir is a potent antiviral medication classified as a nucleoside analog. It is primarily used for the treatment of chronic hepatitis B virus (HBV) infection.
Hepatitis B is a viral infection that attacks the liver, potentially leading to severe liver damage, cirrhosis, or liver cancer. Entecavir works by blocking the action of the enzyme HBV DNA polymerase, which is essential for the virus to replicate and spread. By preventing viral replication, Centaurus tablets help reduce the viral load in the body, slow down liver damage, and improve liver function.
Centaurus tablets are commonly prescribed for both treatment-naive patients (those who haven’t used other HBV treatments) and for patients resistant to other antiviral therapies. It is often recommended as a long-term treatment, and regular monitoring of liver function and viral load is essential during therapy.
The medication is generally well-tolerated, but like all medications, it may cause side effects in some individuals. It is essential to follow the prescribed dosage and administration guidelines to achieve the best treatment outcomes.
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Centaurus 0.5 mg tablets contain Entecavir, an antiviral medication used to manage chronic hepatitis B virus (HBV) infections. Entecavir belongs to the class of drugs known as nucleoside reverse transcriptase inhibitors (NRTIs), which work by inhibiting the replication of HBV, thereby reducing the viral load in the body and minimizing liver damage. citeturn0search8
Uses:
- Chronic Hepatitis B Treatment: Centaurus tablets are prescribed for adults and children (aged 2 years and older, weighing at least 10 kilograms) with chronic HBV infection to decrease the amount of virus in the body and improve liver function. citeturn0search9
Dosage and Administration:
- Dosage: The typical dose is 0.5 mg taken orally once daily on an empty stomach (at least 2 hours after a meal and 2 hours before the next meal). Dosage may vary based on individual factors; follow your healthcare provider’s instructions.
- Administration: Swallow the tablet whole with water. Consistency in timing helps maintain stable drug levels in the body. citeturn0search2
Mechanism of Action:
Entecavir inhibits the HBV reverse transcriptase enzyme, essential for viral replication. By interfering with viral DNA synthesis, it reduces HBV levels, aiding in liver health improvement. citeturn0search2
Side Effects:
Common side effects may include:
- Headache
- Fatigue
- Dizziness
- Nausea
- Stomach pain
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Serious side effects, though rare, can occur:
- Lactic Acidosis: Symptoms include unusual muscle pain, trouble breathing, stomach pain with nausea, vomiting, or irregular heartbeat.
- Severe Liver Problems: Watch for symptoms like jaundice (yellowing of skin or eyes), dark urine, or persistent nausea.
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Seek immediate medical attention if serious side effects occur.
Precautions:
- Allergies: Inform your doctor of any known allergies to Entecavir or other medications.
- Medical History: Disclose any history of kidney problems, liver issues, or HIV infection.
- Pregnancy and Breastfeeding: Discuss potential risks and benefits with your healthcare provider.
- Infection Control: Entecavir does not prevent the transmission of HBV to others. Practice appropriate measures to prevent spreading the virus.
Drug Interactions:
Inform your doctor about all medications, supplements, and herbal products you are taking to avoid potential interactions.
Storage:
- Store at room temperature, away from moisture and heat.
- Keep out of reach of children.
Conclusion:
Centaurus 0.5 mg tablets (Entecavir) are effective in managing chronic hepatitis B infections by reducing viral load and improving liver function. Adherence to the prescribed regimen and regular medical follow-up are essential for optimal outcomes. Always consult your healthcare provider for personalized advice and report any side effects promptly.
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