Empagen Tablets 25mg(Empaglifozin) 14 Film Coated Tablets

Description

Detailed Note on Empagen 25 mg Tablets

1. Introduction: Empagen 25 mg Tablets contain Empagliflozin, which is an oral antidiabetic medication belonging to the class of Sodium-Glucose Co-Transporter 2 (SGLT2) Inhibitors. It is primarily used to manage blood sugar levels in individuals with type 2 diabetes mellitus (T2DM).

2. Composition:

• Active Ingredient: Empagliflozin 25 mg
• Excipients: May include microcrystalline cellulose, magnesium stearate, and other inactive ingredients.

3. Therapeutic Uses: Empagen 25 mg Tablets are indicated for the following purposes:

• Management of Type 2 Diabetes Mellitus (T2DM) to improve glycemic control
• Cardiovascular Risk Reduction in adults with T2DM and established cardiovascular disease
• Chronic Kidney Disease (CKD) to reduce the risk of progression of kidney disease and cardiovascular events

4. Mechanism of Action: Empagliflozin works by inhibiting the SGLT2 protein in the kidneys, which reduces glucose reabsorption and increases glucose excretion through urine. This mechanism leads to a decrease in blood sugar levels.

5. Dosage and Administration:

• Recommended dose: 25 mg once daily
• Can be taken with or without food
• Dose adjustment may be necessary based on individual response and tolerance

6. Side Effects: Common side effects may include:

• Urinary tract infections (UTIs)
• Increased urination
• Thirst
• Hypotension
• Genital infections (e.g., yeast infections)

7. Precautions and Warnings:

• Renal Impairment: Dose adjustments may be required in patients with reduced kidney function
• Ketoacidosis: Monitor for signs of ketoacidosis, particularly in patients with risk factors
• Hypotension: Risk of dehydration and low blood pressure, especially in elderly patients
• Urinary Tract and Genital Infections: Increased risk of infections due to glucosuria

8. Drug Interactions:

• May enhance the diuretic effect, leading to dehydration
• Caution when used with insulin or insulin secretagogues to prevent hypoglycemia
• Reduced effectiveness if used with strong inducers of metabolism enzymes (e.g., rifampin)

9. Storage Conditions:

• Store at room temperature (15°C to 30°C)
• Keep in a dry place away from moisture and light
• Keep out of reach of children

10. Conclusion: Empagen 25 mg Tablets are an effective treatment option for type 2 diabetes mellitus, particularly in patients at risk for cardiovascular events or kidney disease progression. Regular monitoring and follow-ups with a healthcare provider are recommended to ensure safety and optimal therapeutic outcomes.