Clopid 75/75 Tablets (Clopidogrel And Aspirin Tablets) 20 Film Coated Tablets
Clopid AS 75/75 Tablets: Description
Clopid AS 75/75 Tablets are a combination medication containing Clopidogrel (75 mg) and Aspirin (75 mg). Both are antiplatelet agents that work together to prevent the formation of blood clots.
- Clopidogrel is an ADP receptor inhibitor that prevents platelets from sticking together, reducing the risk of blood clots.
- Aspirin is a non-steroidal anti-inflammatory drug (NSAID) that works by blocking the enzyme cyclooxygenase (COX-1), which reduces the formation of thromboxane A2, a substance that promotes platelet aggregation.
By combining these two medications, Clopid AS offers a dual antiplatelet effect, reducing the likelihood of blood clots in blood vessels. This helps prevent severe cardiovascular events such as:
- Heart Attacks
- Strokes
- Blood Clots in Patients with Heart Disease
It is commonly prescribed for individuals with a history of acute coronary syndrome (ACS), myocardial infarction, ischemic stroke, or peripheral arterial disease. Regular use under medical supervision is essential to minimize the risk of life-threatening cardiovascular complications.
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Clopid AS 75mg/75mg Tablet is a combination medication containing two antiplatelet agents: Aspirin (75 mg) and Clopidogrel (75 mg). This formulation is primarily used to prevent the formation of harmful blood clots, thereby reducing the risk of heart attacks and strokes in individuals with cardiovascular conditions.
Mechanism of Action:
- Aspirin: Functions by irreversibly inhibiting cyclooxygenase-1 (COX-1), leading to a decrease in thromboxane A₂ production. This inhibition prevents platelet aggregation, reducing clot formation.
- Clopidogrel: Acts as an adenosine diphosphate (ADP) receptor antagonist. By selectively inhibiting the binding of ADP to its platelet receptor, Clopidogrel impedes platelet activation and aggregation.
The combined action of these two agents provides a synergistic effect in preventing platelet aggregation and thrombus formation.
Indications:
Clopid AS 75mg/75mg Tablet is indicated for:
- Prevention of Heart Attacks and Strokes: Particularly in patients with acute coronary syndrome or those with a history of cardiovascular events.
- Management of Acute Coronary Syndrome (ACS): Including unstable angina and non-ST-segment elevation myocardial infarction (NSTEMI).
Dosage and Administration:
- Standard Dosage: One tablet taken orally once daily.
- Administration: It can be taken with or without food. Consistency in administration time each day is recommended for optimal efficacy.
Side Effects:
Common side effects may include:
- Bleeding: Such as bruising, nosebleeds, or prolonged bleeding from cuts.
- Gastrointestinal Discomfort: Including indigestion or abdominal pain.
- Dizziness or Headache: Occasionally reported by patients.
Serious side effects, though rare, require immediate medical attention. These include signs of severe bleeding (e.g., black or tarry stools, vomiting blood) or allergic reactions (e.g., swelling, severe dizziness, difficulty breathing).
Precautions:
- Bleeding Risk: Due to its antiplatelet properties, there is an increased risk of bleeding. Caution is advised when engaging in activities that may increase the risk of bleeding or injury.
- Surgical Procedures: Inform healthcare providers about this medication before any surgery or dental procedures.
- Alcohol Consumption: Alcohol may increase the risk of gastrointestinal bleeding; thus, limiting or avoiding alcohol is recommended.
- Pregnancy and Breastfeeding: Consult a healthcare provider before use, as this medication may not be recommended during pregnancy or lactation.
Drug Interactions:
Clopid AS 75mg/75mg Tablet may interact with:
- Other Anticoagulants or Antiplatelet Drugs: Increasing bleeding risk.
- Nonsteroidal Anti-Inflammatory Drugs (NSAIDs): May enhance gastrointestinal bleeding risk.
- Selective Serotonin Reuptake Inhibitors (SSRIs): Potentially increasing bleeding tendencies.
Storage:
Store the tablets at room temperature, away from moisture and heat. Keep out of reach of children.
Conclusion:
Clopid AS 75mg/75mg Tablet is an effective combination therapy for reducing the risk of thrombotic cardiovascular events. Adherence to prescribed guidelines and regular consultation with healthcare providers are essential to ensure safety and efficacy.
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